Ep. 110: The True Cause of Insulin Resistance and Diabetes from the Bioenergetic View
The Energy Balance Podcast - Een podcast door Jay Feldman Wellness

In this episode we discuss: Why insulin resistance and diabetes are not caused by excess carbohydrate consumption and are not actually an insulin signaling problem The problems with the idea of metabolic flexibility, earning your carbs, and the carb-insulin model of obesity Why carbs are beneficial even for people who have insulin resistance or diabetes The role of fat burning and stress in driving insulin resistance Specific diet, movement, and supplement recommendations to reverse insulin resistance and diabetes Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/ Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/ Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-110-the-true-cause-of-insulin-resistance-and-diabetes-from-the-bioenergetic-view/ Timestamps: 0:00 – intro 1:14 – metabolic flexibility, earning your carbs, the carb-insulin model of obesity, and dispelling other common insulin resistance myths 7:48 – low-carb, keto, and carnivore diets may improve symptoms but are not the solution for insulin resistance 13:13 – what the mainstream views of insulin resistance gets wrong when it comes to what causes insulin resistance 15:50 – why you might not want to use a continuous glucose monitor and the unnecessary fear of blood glucose spikes 17:48 – whether insulin is harmful and whether we want to keep insulin levels as low as possible 22:15 – whether we can restore optimal insulin sensitivity without low-carb diets 25:16 –the bioenergetic view of insulin resistance 27:12 – insulin resistance as an adaptive evolutionary process that is crucial for survival 31:22 – the difference between physiological and pathological insulin resistance 34:40 – how inhibited glucose oxidation causes insulin resistance 40:46 – how fatty acid oxidation causes increased production of ROS, slows cellular respiration, and blocks glucose oxidation (The Randle Cycle) 51:06 – the harms of ROS production from fatty acid oxidation and other forms of stress 53:04 – insulin resistance as an energy deficient state 54:19 – insulin resistance is not an insulin signaling problem, it’s an energy production problem 58:30 – the role of stress hormones (like cortisol) in insulin resistance 1:02:09 – how insulin and carbohydrates decrease stress 1:05:59 – how to fix insulin resistance and restore insulin sensitivity by fixing our capacity to produce energy 1:10:38 – specific diet, movement, and supplementation recommendations for insulin resistance and diabetes 1:17:55 – why you don’t need to tailor your carb intake to your carb tolerance